Side Effect: Burning sensation in the mouth (glossodynia)

What is a Burning sensation in the mouth (glossodynia)?

Having a burning sensation in the mouth is also known as glossodynia, or burning mouth syndrome (BMS).

BMS is a painful condition that may affect:

• the tongue
• lips
• gums
• palate
• throat
• Or, the entire mouth

What does a Burning sensation in the mouth (glossodynia) look like?

Patients with BMS may describe the sensation as a burning, tingling, numbness, or metallic taste in the mouth without any visible signs of irritation or inflammation.

The sensation may be continuous or intermittent and can vary in severity.

Who gets a Burning sensation in the mouth (glossodynia)?

• Patients with cancer who are undergoing chemotherapy or radiation therapy can be at risk for developing BMS.
• Chemotherapy-induced BMS is thought to be related to damage to the nerves that control taste and sensation in the mouth.
• Radiation-induced BMS may be caused by damage to the salivary glands or nerves in the head and neck region.

How to prevent Burning sensation in the mouth (glossodynia)

• It is essential to maintain good oral hygiene and avoid hot, spicy, acidic, or crunchy foods that can irritate the mouth.
• Patients should also drink plenty of water and use saliva substitutes to help moisten the mouth.
• In addition, dental evaluation and treatment should be performed before cancer treatment to address any existing oral health issues.

How to treat Burning sensation in the mouth (glossodynia)

• Treatment for BMS may involve the use of topical anesthetics, such as lidocaine or benzocaine, to relieve pain and discomfort.
• Saliva substitutes can be used to relieve dry mouth symptoms as well if present.
• Other treatments may include antianxiety medications, antidepressants, and anticonvulsants such as:
  • Amitriptyline (Elavil®)
  • Nortriptyline (Pamelor®)
  • Clonazepam (Klonopin®)
  • Chlordiazepoxide (Librium®)
  • Gabapentin (Neurontin®)

In cases where supportive care measures are not successful, adjusting the dose of the offending agent or switching to an alternative therapy may be necessary to help alleviate symptoms of burning mouth.